When your child has a fever, a sore throat, or a scraped knee that won’t stop crying, ibuprofen, a nonsteroidal anti-inflammatory drug used to reduce pain, fever, and inflammation in children. Also known as children's Motrin, it's one of the most common over-the-counter pain relievers parents reach for—but giving it wrong can be dangerous. Unlike acetaminophen, ibuprofen works by blocking enzymes that cause swelling and pain, making it especially useful for inflammation-related discomfort like ear infections or sprains. But it’s not a one-size-fits-all solution, especially for young kids.
Pediatric ibuprofen dosage, the correct amount of ibuprofen given to children based on weight and age is critical. Giving too much can damage the stomach lining, kidneys, or even cause internal bleeding. The American Academy of Pediatrics says you should never give ibuprofen to babies under 6 months unless a doctor says so. For older kids, the dose isn’t based on age alone—it’s based on weight. A 20-pound child needs a completely different amount than a 60-pound child. Many parents guess, use adult pills, or double up because they’re worried it’s not working. That’s when things go wrong. Always check the label, use the measuring tool that comes with the bottle, and never use a kitchen spoon.
Ibuprofen side effects, common and serious reactions that can occur when children take ibuprofen improperly include upset stomach, vomiting, dizziness, and in rare cases, kidney issues or allergic reactions. If your child has asthma, a history of stomach ulcers, or dehydration, ibuprofen might not be safe at all. And if they’re sick with chickenpox or the flu, ibuprofen can increase the risk of rare but serious skin infections. That’s why some doctors recommend acetaminophen first for fever in young kids—it’s gentler on the stomach and doesn’t carry the same infection risks.
There are times when ibuprofen isn’t the best choice. For teething pain, a cold washcloth or gentle gum massage often works better. For mild headaches or low-grade fevers, rest and fluids might be all your child needs. And if your child is vomiting or not drinking enough, ibuprofen can make dehydration worse. Always watch for signs like dry lips, no tears when crying, or fewer wet diapers. Those are red flags.
What you’ll find below are real, practical guides from parents and doctors who’ve been there. You’ll see how to tell the difference between normal fever and something more serious, why some kids react badly to ibuprofen while others don’t, and what to use instead when it’s not safe. You’ll also learn how to read labels correctly, avoid dangerous mix-ups with other meds, and when to call the pediatrician instead of reaching for the bottle. This isn’t about guessing. It’s about knowing exactly what to do—so you can help your child feel better without risking their health.