DMSO (dimethyl sulfoxide) is a clear solvent that also moves through skin easily. People know it for carrying other drugs through the skin, easing inflammation, and helping with certain medical and lab tasks. You’ve probably seen it mentioned in forums or heard vets talk about it. This page explains the main uses, how it works, and what to watch out for.
Topical pain and inflammation: DMSO is used on skin to reduce pain and swelling in joints and muscles. It can feel cooling at first and then warm as blood flow changes. Some arthritis patients report relief when other options failed.
Drug enhancer: DMSO helps other medicines penetrate the skin. That makes it useful in research and some clinical settings for delivering drugs without injections. Doctors use it carefully because it can also carry unwanted chemicals into the body.
Veterinary use: Vets use DMSO for horses and dogs, often for swelling, bruises, and topical drug delivery. It’s common in equine care after injury, where quick anti-inflammatory action matters.
Cryoprotection and labs: In the lab, DMSO protects cells during freezing. It prevents ice crystals that would damage cell membranes. That’s why it’s common in cell banking, IVF labs, and research that stores cells long term.
Industrial and cleaning solvent: DMSO dissolves many compounds that water won’t. Industries use it for chemical reactions and as a solvent in manufacturing and analytics.
DMSO can change how something smells or tastes because it carries substances into the body. If you apply DMSO, anything on your skin can go inside faster — creams, lotions, or contaminants. Wash the area first and use pure products.
Side effects include skin irritation, itching, redness, and a garlic-like taste or breath after use. Rarely, allergic reactions or eye irritation happen. Don’t use it near the eyes or on open wounds unless a clinician says so.
Dosage varies by use. For topical treatment people often use 50% to 90% solutions, but concentration and frequency should follow medical advice. Lab and cryo uses follow strict protocols and safety rules; don’t try those at home.
Drug interactions: Because DMSO changes absorption, it can raise blood levels of drugs applied with it. That can increase side effects or toxicity. Tell your provider about all medicines and supplements before using DMSO.
Legal and sourcing tips: In many places DMSO is available as a reagent or veterinary product, not always as an approved human medicine. Buy from reputable suppliers, check labels for purity, and avoid industrial-grade DMSO for medical use.
Bottom line: DMSO has real uses—from easing inflammation to protecting cells in labs—but it’s powerful and carries risks. Talk with a healthcare professional or vet before trying it, follow cleaning and dosing advice, and use only quality products.
If you’re researching DMSO for a specific condition, ask for peer-reviewed sources or clinical guidance — that helps separate hype from real evidence and protect your health. Always.